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Page history last edited by PBworks 15 years, 7 months ago

Multiple Sequence Alignment


Multiple Sequence Alignment or MSA's are very important for analysis. Generally you take a group of similar proteins, align protein sequences (or DNA) and look for amino acids that are conserved. This can give you a hint as to what residues are important. This information can be tied together with any structures that exist for your protein family and you can start to get an understanding of what makes the protein work.


Multiple Sequence alignment programs:


Clustal X - a very common MSA tool.

MultiSeq - unifying sequence and structure data for evolutionary analysis



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